From the LSD-bound crystal composition, the facet chain with the lid residue L209EL2 varieties comprehensive hydrophobic contacts with the two LSD and encompassing residues in TMs III, IV, and V (Determine 4C). If the lid moved aside to expose the binding pocket in simulation, various of such contacts broke. We https://baidubookmark.com/story19428042/lsd-crystal-for-dummies