Ketoconazole Coadministration of bosentan a hundred twenty five mg two times daily and ketoconazole, a potent CYP3A inhibitor, greater the plasma concentrations of bosentan by somewhere around a hundred% in standard volunteers. No dose adjustment of bosentan is critical, but amplified effects of bosentan really should be deemed. Notes: Deal https://finnkpsok.blogstival.com/48379067/bosentan-things-to-know-before-you-buy